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Cell & Molecular Biology
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The Phosphothreonine Lyase Activity of a Bacterial Type III Effector Family
- H. Li, H. Xu, Y. Zhou, J. Zhang, C. Long, S. Li, S. Chen, J.-M. Zhou, F. Shao,
- Original article citation: Science 315," 1000 - 1003, (2007).
- Categories: Cell & Molecular Biology
- Recommended by: Timon Cheng-Yi Liu on 11/23/2007 08:51AM GMT
- Reasons for recommending:
Pathogenic bacteria can inject into host cells virulence factors via the so-called type III machinery. Li et al. describe a family of bacterial virulence factors that have a previously unknown phosphothreonine lyase activity that can remove the phosphate from signaling mitogen-activated protein kinase family members involved in innate immunity. This family of effectors is important in the virulence of a variety of animal and plant bacterial pathogens, including Shigella, Salmonella, and Pseudomonas syringae.
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Good Luck!
Very Interesting Work!
This study shows that OspF irreversibly removed phosphate groups from the phosphothreonine but not from the phosphotyrosine residue in the activation loop of MAPKs.This has never been reported previously.
Very Interesting Work!
Interesting Work!
Interesting Work!
It is sure an enligtening article.
It is sure an enlightening article.
good job, very interesting work.
Good job, perfect work.
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Great work!
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helpful article!
good!!!
a very interesting work
Good job, perfect work Interesting Work! good luck
good job, goodluck
good luck!Qiao Zhengzhong
an instructive work
very interesting work
Interesting Work!
very interesting!
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great work!
An Intersting Work！
Very Interesting Work!
very interesting
Interesting Work!
It is sure an very enlightening and interesting Work!
very well done!
Very Interesting Work!
Very Interesting Work!
well done,a creative work
orz
Both the original article and the recomending paper are creative.
Thanks for learning much from such a work!
Very Interesting Work!
yes, indeed very useful and important discovery.
we should support the important articles in order to populize the science into our society.this is the good example
very well done
Good paper!