Method of the Year 2009

  • Cell biology

    • Controlling cell function with light

      • Original article citation: Nat Meth 6," 36 - 36, (2009).
      • Categories: Cell biology, Biotechnology, Neuroscience, and Imaging
      • Recommended by: Daniel Evanko on 07/23/2009 04:22PM GMT
      • Reasons for recommending:
        For the last two years our Methods to Watch section has highlighted the increasing use of light to control cellular function, particularly through the use of light-activated channelrhodopsin-2 to control neuronal signaling. New light-activated proteins have been described and the methodology has resulted in what almost seems to be a flood of papers in top-tier journals reporting biological findings coming from these methods. And the complementary technique, optical uncaging, also continues to thrive. Have these methodologies proven their potential to be Method of the Year 2009?

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