Method of the Year 2009

  • Proteomics

    • Top-down mass spectrometry

      • Original article citation: Nat Meth 5," 24 - 24, (2008).
      • Categories: Proteomics, Biotechnology, Protein biochemistry, and Cell biology
      • Recommended by: Allison Doerr on 07/27/2009 01:57PM GMT
      • Reasons for recommending:
        Top-down mass spectrometry was selected as a Method to Watch at the end of 2007. This tool is particularly useful for analyzing protein post-translational modifications, but it is not yet a high-throughput method. Have we seen the developments needed to drive its limits?

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