Method of the Year 2009
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Direct RNA sequencing
- Original article citation: Nature 461," 814 - 818, (2009).
- Categories: Others, Genetics and genomics, Cell biology, and Synthetic biology
- Recommended by: Bekir Ulker on 11/03/2009 06:10PM GMT
- Reasons for recommending:
Direct RNA sequencing without converting RNA to cDNA, a long desired method now on the edge of being readily available to scientists. This method eliminates the biases, complexity and errors introduced by nucleic acid amplification and requires minute amounts of starting RNA material. This method would lead to major surprises and discoveries in RNA processing as well as various RNA species that organisms might have and the biological roles.
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