Method of the Year 2009
In 2007 we chose Next Generation Sequencing.
In 2008 we chose Super-resolution Imaging.
Now it is time for you, our readers, to help us choose the Method of the Year 2009. Just sign in using your free nature.com registration and vote on our Methods to Watch from previous years or a paper that a visitor has recommended.
Alternatively, you can recommend a paper that represents a method you believe came into its own in 2009 and will have a wide-ranging impact on biology. This paper can be any recently published paper from this year or past years published in any journal. Just provide a link to the paper or other online description of the method and vote away!
Want more information or want to comment? Read the editorial or go to our blog methagora and comment.
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Biotechnology
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11+ votes
7- votes
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Quantitative mass spectrometry
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Original article citation: Nat Meth 6," 34 - 34, (2009). - Categories: Proteomics, Biotechnology, Protein biochemistry, and Cell biology
- Recommended by the Editor: Allison Doerr on 07/27/2009 01:46PM GMT
Quantitative mass spectrometry-based proteomics has been increasingly applied on a large scale to address interesting biological questions; we thus selected it as a Method to Watch in 2008. Has the technology matured enough yet to be considered as Method of the Year in 2009, or are further methodological developments still needed? - Comment on this subject: 1 comment made
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29+ votes
16- votes
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Induced pluripotency
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Original article citation: Nat Meth 6," 33 - 33, (2009). - Categories: Stem cells and Biotechnology
- Recommended by the Editor: Natalie de Souza on 07/27/2009 10:25AM GMT
At the end of 2007, the generation of human induced pluripotent stem (iPS) cells brought much promise, but also many questions, to the field of stem cells. There certainly has been a lot of development in this area since then, and it has recently been accelerating rapidly. Enough so that methods to generate iPS cells be named Method of the Year 2009? - Comment on this subject: 0 comments made
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7+ votes
5- votes
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Controlling cell function with light
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Original article citation: Nat Meth 6," 36 - 36, (2009). - Categories: Cell biology, Biotechnology, Neuroscience, and Imaging
- Recommended by the Editor: Daniel Evanko on 07/23/2009 04:22PM GMT
For the last two years our Methods to Watch section has highlighted the increasing use of light to control cellular function, particularly through the use of light-activated channelrhodopsin-2 to control neuronal signaling. New light-activated proteins have been described and the methodology has resulted in what almost seems to be a flood of papers in top-tier journals reporting biological findings coming from these methods. And the complementary technique, optical uncaging, also continues to thrive. Have these methodologies proven their potential to be Method of the Year 2009? - Comment on this subject: 0 comments made
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