User recommended papers
-
Neuroscience
-
1+ votes
0- votes
- Log in to vote
-
Different effects of mild and severe seizures on hippocampal neurogenesis in adult rats
- Fang Yang, Jin-Cun Wang, Jun-Liang Han, Gang Zhao, Wen Jiang,
- Original article citation: Hippocampus doi:10.1002/hipo.20409
- Categories: Neuroscience, Cell & Molecular Biology, and Developmental Biology
- Recommended by: Jie Huang on 02/21/2008 03:47PM GMT
- Reasons for recommending:
Hippocampus is known to be one site of continuing neurogenesis into adulthood for humans and other mammals, which provides possible compensatory and rehabilitative mechanisms for some brain injuries. Based on previous knowledge about epileptic seizures effect on neurogenesis in dentate gyrus (DG), researchers in this study examined seizure severity's influence in this process on rats. It appeared though both mild and severe seizures promoted mitotic activity in DG, difference in severity were driving neuron proliferation and migration into two distinctive directions. On the other hand, it hints at limitations of hippocampus' postnatal neurogenesis.
-
Comments
Reader comments are usually moderated after posting. For more controversial topics, we reserve the right to moderate before comments are published.
Add your own comment
You can be as critical or controversial as you like, but please don't get personal or offensive, and do keep it brief. Remember this is for feedback and discussion - not for publishing papers, press releases or advertisements, for example.
You need to be registered with Nature to leave a comment. Please log in or register as a new user. You will be re-directed back to this page.
