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Cell & Molecular Biology
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Targeted inhibition of HBV gene expression by single-chain antibody mediated small interfering RNA delivery
- Wei-Hong Wen, Jia-Yun Liu, Wei-Jun Qin, Jing Zhao, Tao Wang, Lin-Tao Jia, Yan-Ling Meng, Hui Gao, Cai-Fang Xue, Bo-Quan Jin, Li-Bo Yao, Si-Yi Chen, An-Gang Yang,
- Original article citation: Hepatology 46," 84 - 94, (2007).
- Categories: Cell & Molecular Biology, Biotechnology, and Clinical Medicine
- Recommended by: xue qian on 02/25/2008 09:21AM GMT
- Reasons for recommending:
This paper demonstrates ScFv-Ck-tP mediated RNA interference executes potent and persistent HBV inhibition. The findings will definitely increase the potential of targeted delivery siRNA therapeutics for clinical application in the therapy of hepatitis B.
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This article is very useful to my resaerch.
exploring in HBV is very important for Chinese future.