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Central Amygdala Extracellular Signal-Regulated Kinase Signaling Pathway Is Critical to Incubation of Opiate Craving
- Original article citation: Journal of Neuroscience 28," 13248 - 13257, (2008).
- Categories: Neuroscience and Cell & Molecular Biology
- Recommended by: Xue Yanxue on 12/04/2008 09:12AM GMT
- Reasons for recommending:
Their results indicate that central amygdala ERK activity mediates the incubation of morphine craving, as assessed in the CPP procedure. These results extend previous data on the role of central amygdala ERK in incubation of cocaine craving, as assessed in the self-administration procedure. This generality across drugs and procedures suggest that central amygdala ERK plays a general role in incubation of reward craving. They also found that central amygdala CREB activity is associated with incubation of morphine craving.
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