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A novel redox-potential-based screening strategy for rapid isolation of Klebsiella pneumoniae mutants with enhanced 1,3-propanediol producing capability
- C. Du, Y. Zhang, Y. Li, Z. Cao,
- Original article citation: Applied and Environmental Microbiology doi:10.1128/AEM.02857-06 (2007)
- Categories: Biotechnology and Genetics
- Recommended by: Zheng-Hong Xu on 06/06/2007 09:42AM GMT
- Reasons for recommending:
In many years the Chinese Industrial Biotechnologists spent a lot of energy on increasing the production level of useful metabolites. However, they rarely develop new methodology which would result in a revolutionary development of a certain biotechnological process. Du et al. describes a novel redox-potential-based screening strategy for rapid isolation of Klebsiella pneumoniae mutants with enhanced 1,3-propanediol (a bulk chemical) production capability. The result provides a novel screening strategy which could be helpful to screen/develop strains involved in the oxidoreduction biosynthesis, which is of great potential for industrial biotechnology. The other significance of this study is that it is a typical hypothesis-driven research, which is rarely found in the industrial biotechnology research field in China. The acceptance of this nice article by Applied & Environmental Microbiology symbolizes that the industrial biotechnologists are more focusing on the fundamental research area, e. g. development of novel methodologies. This is important for achieving a bright future for China’s bioeconomy.
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excellent paper will contribute to elevate the level of china's biotechnology