User recommended papers
User-recommended papers allows you to suggest a paper you would like to see on Nature China. When these papers appear on our site, users may comment and vote on them. To recommend a paper please use this form. Please note that you cannot recommend a paper you have authored. The editors will reject any self-recommendations. All comments and recommendation are checked by the editors and may be edited prior to publication on the site.
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8 votes
Neuroscience
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7+ votes
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Auditory fear conditioning modulates prepulse inhibition in socially reared rats and isolation-reared rats.
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Original article citation: Behavioral Neuroscience 122," 107 - 118, (2008). - Categories: Neuroscience
- Recommended by : Chun Wang on 07/30/2008 08:05PM GMT
This fascinating study for the first time shows that isolation rearing could not only impair prepulse inhibition, a commonly used sensorimotor gating model of schizophrenia, but also significantly impair the attentional modulation of prepulse inhibition. The authors further demonstrate that this effect is modulated via metabolic glutamate receptors. This work provides a brand new animal model for investigating both neural bases and cognitive features of schizophrenia. - Comment on this subject: 0 comments made
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15 votes
Physics
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15+ votes
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Attosecond ionization gating for isolated attosecond electron wave packet and broadband attosecond xuv pulses
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Original article citation: Phys. Rev. A 76," (2007). - Categories: Physics and Chemistry
- Recommended by : Feng He on 04/17/2008 08:29PM GMT
Attosecond laser pulse is the most fast camera, with which people can capture the electron motion inside the atom or molecule. However, it's a big challenge to generate ultrashort, high power attosecond pulses. In this paper, Pengfei Lu et.al. present an interesting strategy to obtain an isolated attosecond pulse, which could be realized in the current laser technology. For this reason, I strongly recommend this paper to be appeared in Nature China. - Comment on this subject: 2 comments made
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2 votes
Ecology & Evolution
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2+ votes
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Chloroplast phylogeography of Dipentodon (Dipentodontaceae) in southwest China and northern Vietnam
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Original article citation: Mol Ecol 17," 1054 - 1065, (2008). - Categories: Ecology & Evolution, Genetics, and Cell & Molecular Biology
- Recommended by : zhang xuemei on 04/12/2008 02:13AM GMT
This is an excellent and meaningful papar involving the conceivably most complicated evolutionary history in the southeast Tibetan Plateau,where the topography and climate are extremely complex. The incumbent target is also an attractive monotypic genus Dipentodon sinicus. By using chloroplast sequences, important results were obtained providing new insights to the evolution of biodiversity on the Tibetan Plateau and adiacent areas. Also, a historical framework for the conservation of biodiversity in this area was given. In summary, it is an informative and helpful paper for understanding the Dipentodon and Tibetan Plateau. - Comment on this subject: 0 comments made
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4 votes
Neuroscience
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4+ votes
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Whole brain functional connectivity in the early blind
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Original article citation: Brain 130," 2085 - 2096, (2007). - Categories: Neuroscience
- Recommended by : Yong HE on 04/07/2008 09:45AM GMT
Recent research has demonstrated that visual deprivation in early life is accompanied by structural and functional alterations of the brain, which could be explained by either of two hypotheses. The general-loss hypothesis might explain for maladaptive changes, while the compensatory-plasticity hypothesis might explain for enhanced ability to use remaining senses. So far, task-based fMRI studies have provided support for the compensatory-plasticity hypothesis, but these studies did not provide evidence supporting the general-loss hypothesis since the blind people cannot carry out visual tasks. Liu et al. employed resting-state fMRI to investigate the changes in functional connectivity of spontaneous brain activities in early blind subjects. They found that, compared with controls, the blind demonstrated decreased functional connectivities within the occipital visual cortices as well as between the occipital visual cortices and the parietal somatosensory, frontal motor and temporal multisensory cortices. The authors interpret these differences as supporting the general-loss hypothesis. In addition, they also found that the introduction of Braille earlier in life or with longer daily practice sessions was associated with stronger functional connectivities between these brain areas, which might support the compensatory-plasticity hypothesis. Finally, the authors also report increased functional connectivities between occipital cortices and frontal cortices in subjects with early onset of blindness as compared to the controls, which they again interpret as evidence for the compensatory plasticity. This study indicates that the changes in the functional connectivities in the resting state may be an integrated reflection of general loss and compensatory plasticity when a single sensory modality is deprived. - Comment on this subject: 0 comments made
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2 votes
Clinical Medicine
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2+ votes
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Discussion of posthumous organ donation in Chinese families
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Original article citation: Psych., Hlth. & Med. 13," 48 - 54, (2008). - Categories: Clinical Medicine
- Recommended by : Jie Huang on 04/04/2008 04:26PM GMT
A pretty cool investigation about organ donation in China's background. Organ donation is more prevelant in western cultures, at least it's an ordinary topic for them, e.g., when applying for a driver's license, there's a check-box on the application form for you to indicate whether you are willing to donate your organs if "something" happens. In China, it's more of problem with family and social pressure coming from traditional concept. Based on the perspective of psychology, they investigated the factors affecting the likelihood of family discussion about organ donation. It serves socially pragmatic value for medical service. - Comment on this subject: 0 comments made
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1 vote
Neuroscience
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1+ votes
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Ipsilateral brain deactivation specific to the nondominant hand during simple finger movements
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Original article citation: Neuroreport 19," 483 - 486, (2008). - Categories: Neuroscience
- Recommended by : Jie Huang on 03/26/2008 06:35PM GMT
Independent of handness, their data showed a deactivation at ipsilateral primary motor cortex corresponding to finger movement of nondominant hand, which was not seen for dominant hand. The pattern suggested functional asymmetry of motor cortices on two hemispheres. An interesting topic would be to look into how this asymmetry is related to previous hand-using experience. - Comment on this subject: 0 comments made
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2 votes
Cell & Molecular Biology
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2+ votes
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Targeted inhibition of HBV gene expression by single-chain antibody mediated small interfering RNA delivery
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Original article citation: Hepatology 46," 84 - 94, (2007). - Categories: Cell & Molecular Biology, Biotechnology, and Clinical Medicine
- Recommended by : xue qian on 02/25/2008 09:21AM GMT
This paper demonstrates ScFv-Ck-tP mediated RNA interference executes potent and persistent HBV inhibition. The findings will definitely increase the potential of targeted delivery siRNA therapeutics for clinical application in the therapy of hepatitis B. - Comment on this subject: 2 comments made
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0 votes
Neuroscience
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0+ votes
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Spontaneous activities associated with primary visual cortex: detected from resting state fMRI data
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Original article citation: Cerebral Cortex 18," 697 - 704, (2008). - Categories: Neuroscience
- Recommended by : Meng Liang on 02/24/2008 04:02PM GMT
Using regional temporal clustering, this study provided quantitative evidence for the existence of spontaneous activities in the primary visual areas of human beings during the resting state. They also found that there was a neural network that was associated with the emergence of spontaneous activities in the PVA. Although the precise mental processes supported by such a neural network remain to be elucidated, our results suggest that memory-related mental imagery and visual memory consolidation processes may be candidates. Through investigating spontaneous activities without any external stimulus, this study may offer a new perspective for exploring the visual perception and other brain processing. In addition, the phenomenon that primary visual area has spontaneous activities without any stimulus offers new evidence for the perspective that the brain is a system intrinsically operating on its own, and sensory information interacts with rather than determines the operation of the system. - Comment on this subject: 0 comments made
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1 vote
Cell & Molecular Biology
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1+ votes
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SIRT1 Improves Insulin Sensitivity under Insulin-Resistant Conditions by Repressing PTP1B
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Original article citation: Cell Metabolism 6," 307 - 319, (2007). - Categories: Cell & Molecular Biology, Genetics, and Clinical Medicine
- Recommended by : yunbiao lu on 02/22/2008 12:37PM GMT
just like the author said: the finding that SIRT1 improves insulin sensitivity has implications toward resolving insulin resistance and type 2 diabetes. - Comment on this subject: 0 comments made
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1 vote
Neuroscience
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1+ votes
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Different effects of mild and severe seizures on hippocampal neurogenesis in adult rats
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Original article citation: Hippocampus doi:10.1002/hipo.20409 - Categories: Neuroscience, Cell & Molecular Biology, and Developmental Biology
- Recommended by : Jie Huang on 02/21/2008 03:47PM GMT
Hippocampus is known to be one site of continuing neurogenesis into adulthood for humans and other mammals, which provides possible compensatory and rehabilitative mechanisms for some brain injuries. Based on previous knowledge about epileptic seizures effect on neurogenesis in dentate gyrus (DG), researchers in this study examined seizure severity's influence in this process on rats. It appeared though both mild and severe seizures promoted mitotic activity in DG, difference in severity were driving neuron proliferation and migration into two distinctive directions. On the other hand, it hints at limitations of hippocampus' postnatal neurogenesis. - Comment on this subject: 0 comments made
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