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User-recommended papers allows you to suggest a paper you would like to see on Nature China. When these papers appear on our site, users may comment and vote on them. To recommend a paper please use this form. Please note that you cannot recommend a paper you have authored. The editors will reject any self-recommendations. All comments and recommendation are checked by the editors and may be edited prior to publication on the site.

• Biotechnology

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  • Targeted inhibition of HBV gene expression by single-chain antibody mediated small interfering RNA delivery

    • Wei-Hong Wen, Jia-Yun Liu, Wei-Jun Qin, Jing Zhao, Tao Wang, Lin-Tao Jia, Yan-Ling Meng, Hui Gao, Cai-Fang Xue, Bo-Quan Jin, Li-Bo Yao, Si-Yi Chen, An-Gang Yang
      Original article citation: Hepatology 46," 84 - 94, (2007).

    • Categories: Cell & Molecular Biology, Biotechnology, and Clinical Medicine
    • Recommended by : xue qian on 02/25/2008 09:21AM GMT
      
      This paper demonstrates ScFv-Ck-tP mediated RNA interference executes potent and persistent HBV inhibition. The findings will definitely increase the potential of targeted delivery siRNA therapeutics for clinical application in the therapy of hepatitis B.
    • Comment on this subject: 2 comments made

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  • Bipartite network projection and personal recommendation

    • Tao Zhou, Jie Ren, Matúš Medo, Yi-Cheng Zhang
      Original article citation: Phys. Rev. E 76," (2007).

    • Categories: Physics and Biotechnology
    • Recommended by : Da-Ren He on 02/19/2008 12:36AM GMT
      
      This paper proposes a new information processing method which is applicable to situations in many scientific disciplines, especially for recommendation systems.
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  • A Facile Method for Permanent and Functional Surface Modification of Poly(dimethylsiloxane)

    • Y. Wu, Y. Huang, H. Ma
      Original article citation: J. Am. Chem. Soc. 129," 7226 - 7227, (2007).

    • Categories: Biotechnology, Materials, Chemistry, and Clinical Medicine
    • Recommended by : Jeff Xi on 11/15/2007 01:12AM GMT
      
      This article demonstrated a novel strategy to realize the surface modification of PDMS, which rendered PDMS tunable surface properties, for example, from very hydrophilic to very hydrophobic.
    • Comment on this subject: 1 comment made

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  • Nano-effects, quantum-like properties in electrospun nanofibers

    • J HE, Y WAN, L XU
      Original article citation: Chaos, Solitons & Fractals 33," 26 - 37, (2007).

    • Categories: Materials, Biotechnology, and Physics
    • Recommended by : Yong Liu on 11/15/2007 12:32AM GMT
      
      It is an excellent papers in nanoscience field. This research reveals that fascinating phenomena arise when the diameter of the electrospun nanofibers is less than 100 nm. The nano-effect has been demonstrated for unusual strength, high surface energy, surface reactivity, high thermal and electric conductivity. Dragline silk is made of many nano-fibers with diameter of about 20 nm, thus it can make full use of nano-effects. It is a challenge to developing technologies capable of preparing for nanofibers within 100 nm.
    • Comment on this subject: 0 comments made

  • • 1+ votes

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  • Mapping the C. elegans noncoding transcriptome with a whole-genome tiling microarray

    • H. He, J. Wang, T. Liu, X. S. Liu, T. Li, Y. Wang, Z. Qian, H. Zheng, X. Zhu, T. Wu, B. Shi, W. Deng, W. Zhou, G. Skogerbo, R. Chen
      Original article citation: Genome Research 17," 1471 - 1477,

    • Categories: Genetics, Biotechnology, and Cell & Molecular Biology
    • Recommended by : Xuegong Zhang on 11/14/2007 01:15PM GMT
      
      This paper presents a major breakthrough in the study of non-coding RNAs in C. elegans, and also stands as an excellent example of the integration of computation analysis and bench experiments.
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  • • 1+ votes

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  • Prevention of neuropathic pain in an animal model of spare nerve injury following oral immunization with recombinant adenovirus serotype 5-mediated NR2B gene transfer

    • G-M Wang, X-B Tian, J-P Chen, S-B Yang, F Gao, H Yang, K An, Y-K Tian
      Original article citation: Gene Ther doi:10.1038/sj.gt.3303025 (2007)

    • Categories: Clinical Medicine, Genetics, Neuroscience, and Biotechnology
    • Recommended by : wei zeng on 11/01/2007 06:27AM GMT
      
      This paper investigated the effect of oral immunization with recombinant adenovirus serotype 5-mediated NR2B gene transfer (rAd5/NR2B) for the modulation of neuropathic pain.
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  • • 23+ votes

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  • A novel redox-potential-based screening strategy for rapid isolation of Klebsiella pneumoniae mutants with enhanced 1,3-propanediol producing capability

    • C. Du, Y. Zhang, Y. Li, Z. Cao
      Original article citation: Applied and Environmental Microbiology doi:10.1128/AEM.02857-06 (2007)

    • Categories: Biotechnology and Genetics
    • Recommended by : Zheng-Hong Xu on 06/06/2007 09:42AM GMT
      
      In many years the Chinese Industrial Biotechnologists spent a lot of energy on increasing the production level of useful metabolites. However, they rarely develop new methodology which would result in a revolutionary development of a certain biotechnological process. Du et al. describes a novel redox-potential-based screening strategy for rapid isolation of Klebsiella pneumoniae mutants with enhanced 1,3-propanediol (a bulk chemical) production capability. The result provides a novel screening strategy which could be helpful to screen/develop strains involved in the oxidoreduction biosynthesis, which is of great potential for industrial biotechnology. The other significance of this study is that it is a typical hypothesis-driven research, which is rarely found in the industrial biotechnology research field in China. The acceptance of this nice article by Applied & Environmental Microbiology symbolizes that the industrial biotechnologists are more focusing on the fundamental research area, e. g. development of novel methodologies. This is important for achieving a bright future for China’s bioeconomy.
    • Comment on this subject: 1 comment made

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