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User-recommended papers allows you to suggest a paper you would like to see on Nature China. When these papers appear on our site, users may comment and vote on them. To recommend a paper please use this form. Please note that you cannot recommend a paper you have authored. The editors will reject any self-recommendations. All comments and recommendation are checked by the editors and may be edited prior to publication on the site.

• Clinical Medicine

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  • Ginsenoside Rg1-induced alterations in gene expression in TNF-α stimulated endothelial cells

    • Shengqi Wang, Junping Lu, Zengchun Ma, Jing Yang, Jian Huang, Shuren Wang
      Original article citation: Chinese Medical Journal 117," 871 - 876, (2004).

    • Categories: Clinical Medicine
    • Recommended by the Editor: Felix Cheung on 02/26/2007 05:54PM GMT
      
      In China, ginseng root began to be used in medicine over 2000 years ago. And its use is gaining popularity in the western world. Ginsenosides are the most important component isolated from ginseng. The authors investigated the effect of ginsenoside Rg1 on the spectrum of gene expression in the endothelial cells stimulated by TNF-alpha, and further explored the potential molecular mechanism of endothelial protection by ginsenoside Rg1.
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  • Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding

    • Francis K.L. Chan
      Original article citation: New England Journal of Medicine 352," 238 - 244, (2005).

    • Categories: Clinical Medicine
    • Recommended by : Chan Martin C.W. on 02/17/2007 03:08PM GMT
      
      This paper challenges the appropriateness of the current clinical guideline to give clopidogrel, a drug aimed to preventing recurrent ulcer, to patients who have substantial gastrointestinal intolerance of aspirin.
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  • Frequency of CYP2D6*10 and *14 Alleles and their Influence on the Metabolic Activity of CYP2D6 in a Healthy Chinese Population

    • W M Cai, B Chen, W X Zhang
      Original article citation: Clin Pharmacol Ther 81," 95 - 98, (2007).

    • Categories: Genetics and Clinical Medicine
    • Recommended by : Tali Swann-Sternberg on 02/08/2007 07:14PM GMT
      
      This is an article on gene allele frequency and drug metabolism in a Chinese population.
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  • Crystal structure of mitochondrial respiratory membrane protein complex II

    • F Sun, X Huo, Y Zhai, A Wang, J Xu, D Su, M Bartlam, Z Rao
      Original article citation: Cell 121," 1043 - 1057, (2005).

    • Categories: Cell & Molecular Biology, Genetics, Chemistry, and Clinical Medicine
    • Recommended by the Editor: Samia Mantoura on 02/08/2007 01:33PM GMT
      
      This paper reports the remarkable achievement of solving the crystal structure of complex II of the mitochondrial respiratory chain, and provides the structural framework for better understanding of the mitochondrial respiratory system and human mitochondrial diseases related to mutations in this complex.
    • Comment on this subject: 1 comment made

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  • Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release

    • W. Lu
      Original article citation: Proceedings of the National Academy of Sciences 103," 12540 - 12545, (2006).

    • Categories: Clinical Medicine and Cell & Molecular Biology
    • Recommended by : Dangsheng Li on 01/31/2007 08:04PM GMT
      
      3a protein is encoded by one of the 14 ORFs of the SARS virus, but its function remained unknown until this study. This paper demonstrates that 3a protein forms an ion channel that functions to promote virus release during SARS infection, and suggests new strategies for treatment of SARS by targeting this ion channel.
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