Recommend a paper
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Genetics
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Interaction of APC/C-E3 ligase with Swi6/HP1 and Clr4/Suv39 in heterochromatin assembly in fission yeast
- Original article citation: Journal of Biological Chemistry doi:10.1074/jbc.M806461200 (2008)
- Categories: Genetics and Cell & Molecular Biology
- Recommended by: Sneh Lata on 01/31/2009 05:53AM GMT
- Reasons for recommending:
This paper for the first time demonstrates a surprising role of Anaphase promoting Complex, APC/C in assembly of heterochromatin and silencing at mating type, centromere and rDNA loci in fission yeat.
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Thanks for recommonding such a nice paper published by Dr. Jagmohan's Group. The findings are really surprising and open a new area of investigation about the synchronisation of cellular events of heterochromatin formation and chromosome seggregation mediated by Aaphase Promoting Complex APC/C.