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User-recommended papers allows you to suggest a paper you would like to see on Nature India. When these papers appear on our site, users may comment and vote on them. To recommend a paper please use this form. Please note that you cannot recommend a paper you have authored. The editors will reject any self-recommendations. All comments and recommendation are checked by the editors and may be edited prior to publication on the site.

• Biotechnology

  • • 29+ votes

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  • Small RNA mediated silencing to target Tomato leaf curl virus

    • Shelly Praveen, S. V. Ramesh, Vikas Koundal, Anil Mishra, R. K. Jain
      Original article citation: J. of Plant Interactions 2," 213 - 218, (2007).

    • Categories: Biotechnology and Cell & Molecular Biology
    • Recommended by : Praveen Mehrotra on 02/25/2008 05:39PM GMT
      
      Targeting viral genome through small RNA mediated strategy is an important tool for developing resistance. Viral derived siRNAs, if delivered through host (indigenous) RNAi machinery in the form of artificial micro RNA, is more effective in producing small RNAs and ultimately the resistance response.
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  • • 3+ votes

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  • Support Vector Machine-based method for predicting subcellular localization of mycobacterial proteins using evolutionary information and motifs

    • Mamoon Rashid, Sudipto Saha, Gajendra PS Raghava
      Original article citation: BMC Bioinformatics 8," 337 , (2007).

    • Categories: Cell & Molecular Biology and Biotechnology
    • Recommended by : Nitish Mishra on 02/09/2008 05:16AM GMT
      
      A new subcellular class of mycobacterial proteins named "membrane-attached by lipid anchor" has been introduced for the first time.
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  • • 2+ votes

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  • Host–virus genome interactions: macro roles for microRNAs

    • Vinod Scaria, Manoj Hariharan, Beena Pillai, Souvik Maiti, Samir K. Brahmachari
      Original article citation: Cell Microbiol 9," 2784 - 2794, (2007).

    • Categories: Cell & Molecular Biology, Biotechnology, Clinical Medicine, and Genetics
    • Recommended by : Klein K on 02/08/2008 05:34AM GMT
      
      This is an interesting review describing the models of host-virus interactions mediated through microRNAs.
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  • • 51+ votes

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  • Hairpin RNA-Mediated Strategies for Silencing of

    • S.V. Ramesh, A.K. Mishra, S. Praveen
      Original article citation: Oligonucleotides 17," 251 - 257, (2007).

    • Categories: Biotechnology and Cell & Molecular Biology
    • Recommended by : Praveen Mehrotra on 02/02/2008 01:29PM GMT
      
      Careful designing of hairpin strategies will not only help in developing trait stable transgenics but will also help in developing broad spectrum resistance against viruses.
    • Comment on this subject: 2 comments made

  • • 5+ votes

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  • microRNAs in viral oncogenesis

    • Vinod Scaria, Vaibhav Jadhav
      Original article citation: Retrovirology 4," 82 , (2007).

    • Categories: Biotechnology, Cell & Molecular Biology, and Genetics
    • Recommended by : Klein K on 01/26/2008 10:33AM GMT
      
      This short review summarises the possible networks of host-pathogen inetractions in microRNA mediated viral oncogenesis. This is a clear starting point for a systems level understanding of the role of microRNAs in viral oncogenesis.
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  • • 6+ votes

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  • Intrinsic disorder in yeast transcriptional regulatory network

    • Gajinder Pal Singh, Debasis Dash
      Original article citation: Proteins 68," 602 - 605, (2007).

    • Categories: Cell & Molecular Biology and Biotechnology
    • Recommended by : Vinod Scaria on 01/18/2008 03:55PM GMT
      
      This paper shows how transcription factors might utilise structural disorder to bind to multiple promoter regions.
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  • • 25+ votes

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  • Host-generated double stranded RNA induces RNAi in plant-parasitic nematodes and protects the host from infection

    • B YADAV, K VELUTHAMBI, K SUBRAMANIAM
      Original article citation: Molecular and Biochemical Parasitology 148," 219 - 222, (2006).

    • Categories: Biotechnology and Cell & Molecular Biology
    • Recommended by : Keerti S. Rathore on 01/17/2008 02:52PM GMT
      
      The study represents a significant piece of research. It shows a novel way to control the problem of parasitic nematodes using the RNAi technology. It is the first of its kind of study showing clearly that just as in the case of C. elegans, vital genes can be silenced in parasitic nematodes by ingestion of double stranded RNA/siRNA.
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