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User-recommended papers allows you to suggest a paper you would like to see on Nature India. When these papers appear on our site, users may comment and vote on them. To recommend a paper please use this form. Please note that you cannot recommend a paper you have authored. The editors will reject any self-recommendations. All comments and recommendation are checked by the editors and may be edited prior to publication on the site.
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Cell & Molecular Biology
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Catechol-estrogen modified DNA: A better antigen for cancer autoantibody
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Original article citation: Archives of Biochemistry and Biophysics 465," 293 - 300, (2007). - Categories: Clinical Medicine and Cell & Molecular Biology
- Recommended by : NAJMUL ISLAM on 02/05/2008 07:06AM GMT
This paper helps in better understanding female sex hormone mediated DNA damage and its role in carcinogenesis as well as autoantibody formation against estrogen modified DNA. - Comment on this subject: 0 comments made
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51+ votes
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Hairpin RNA-Mediated Strategies for Silencing of
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Original article citation: Oligonucleotides 17," 251 - 257, (2007). - Categories: Biotechnology and Cell & Molecular Biology
- Recommended by : Praveen Mehrotra on 02/02/2008 01:29PM GMT
Careful designing of hairpin strategies will not only help in developing trait stable transgenics but will also help in developing broad spectrum resistance against viruses. - Comment on this subject: 2 comments made
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Allicin-induced suppression of Mycobacterium tuberculosis 85B mRNA in human monocytes
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Original article citation: Biochemical and Biophysical Research Communications 355," 471 - 476, (2007). - Categories: Cell & Molecular Biology and Clinical Medicine
- Recommended by : NAJMUL ISLAM on 02/01/2008 03:39PM GMT
It throws some light in suppressing MTB 85B at the gene level by natural antioxidant, namely allicin from garlic, and hence may provide some light in combating TB. - Comment on this subject: 0 comments made
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5+ votes
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microRNAs in viral oncogenesis
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Original article citation: Retrovirology 4," 82 , (2007). - Categories: Biotechnology, Cell & Molecular Biology, and Genetics
- Recommended by : Klein K on 01/26/2008 10:33AM GMT
This short review summarises the possible networks of host-pathogen inetractions in microRNA mediated viral oncogenesis. This is a clear starting point for a systems level understanding of the role of microRNAs in viral oncogenesis. - Comment on this subject: 0 comments made
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6+ votes
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Intrinsic disorder in yeast transcriptional regulatory network
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Original article citation: Proteins 68," 602 - 605, (2007). - Categories: Cell & Molecular Biology and Biotechnology
- Recommended by : Vinod Scaria on 01/18/2008 03:55PM GMT
This paper shows how transcription factors might utilise structural disorder to bind to multiple promoter regions. - Comment on this subject: 0 comments made
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Host-generated double stranded RNA induces RNAi in plant-parasitic nematodes and protects the host from infection
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Original article citation: Molecular and Biochemical Parasitology 148," 219 - 222, (2006). - Categories: Biotechnology and Cell & Molecular Biology
- Recommended by : Keerti S. Rathore on 01/17/2008 02:52PM GMT
The study represents a significant piece of research. It shows a novel way to control the problem of parasitic nematodes using the RNAi technology. It is the first of its kind of study showing clearly that just as in the case of C. elegans, vital genes can be silenced in parasitic nematodes by ingestion of double stranded RNA/siRNA. - Comment on this subject: 0 comments made
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Novel biochemical properties of a CRP/FNR family transcription factor from Mycobacterium tuberculosis
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Original article citation: International Journal of Medical Microbiology 297," 451 - 457, (2007). - Categories: Cell & Molecular Biology, Ecology & Evolution, and Genetics
- Recommended by : Niyaz Ahmed on 01/16/2008 05:59PM GMT
This is an interesting paper that provides a possible framework for better understanding of the stress response in mycobacteria. A genome-scale inventory of such genes across different mycobacteria may be able to highlight the importance of CRP-regulons in pathogenesis. Through a series of mobility shift assays, the authors have proved that the CRP family of putative regulons in fact operate as the DNA binding proteins. It will be interesting to know how these CRP proteins might regulate the expression of virulence genes of especially the latent and dormant mycobacteria in response to a variety of environmental and metabolic signals. - Comment on this subject: 0 comments made
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The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1
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Original article citation: Current Opinion in Genetics & Development 17," 408 - 414, (2007). - Categories: Cell & Molecular Biology and Developmental Biology
- Recommended by : Hemant Purohit on 01/16/2008 11:16AM GMT
The recent advances in analysis of gene regulation and function using microarray data proposes that the decisions at any point in the cells are not made independently by any pathway. It is supposed to be a consensuses generated where the information via different nodes are shared. The global response to any scenario, most likely, is providing the broad picture with defined rules, under the umbrella of which cross talking could ultimately be manifested as the physiology at that point. This paper proposes the option through which gene regulation could be discussed at global level. However, the question will remain: is there a parallel special AT rich binding protein mediated regulation system existing in bacteria or is this a more regulated version that biological systems opted in the evolution? - Comment on this subject: 1 comment made
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