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  • microRNAs in viral oncogenesis

    • Vinod Scaria, Vaibhav Jadhav
      Original article citation: Retrovirology 4," 82 , (2007).

    • Categories: Biotechnology, Cell & Molecular Biology, and Genetics
    • Recommended by : Klein K on 01/26/2008 10:33AM GMT
      
      This short review summarises the possible networks of host-pathogen inetractions in microRNA mediated viral oncogenesis. This is a clear starting point for a systems level understanding of the role of microRNAs in viral oncogenesis.
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  • • 3+ votes

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  • Novel biochemical properties of a CRP/FNR family transcription factor from Mycobacterium tuberculosis

    • Y AKHTER, S TUNDUP, S HASNAIN
      Original article citation: International Journal of Medical Microbiology 297," 451 - 457, (2007).

    • Categories: Cell & Molecular Biology, Ecology & Evolution, and Genetics
    • Recommended by : Niyaz Ahmed on 01/16/2008 05:59PM GMT
      
      This is an interesting paper that provides a possible framework for better understanding of the stress response in mycobacteria. A genome-scale inventory of such genes across different mycobacteria may be able to highlight the importance of CRP-regulons in pathogenesis. Through a series of mobility shift assays, the authors have proved that the CRP family of putative regulons in fact operate as the DNA binding proteins. It will be interesting to know how these CRP proteins might regulate the expression of virulence genes of especially the latent and dormant mycobacteria in response to a variety of environmental and metabolic signals.
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