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Stem cell niches
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Elements of a Neural Stem Cell Niche Derived from Embryonic Stem Cells
- Chris Pierret, Kathleen Spears, Jason A. Morrison, Joel A. Maruniak, Martin L. Katz, Mark D. Kirk,
- Original article citation: Stem Cells and Development 16," 1017 - 1026, (2007).
- Categories: Stem cell niches, Tissue stem cells, Drug discovery, and Research tools
- Recommended by: Raja Radio on 12/27/2007 11:06PM GMT
- Reasons for recommending:
The authors have developed an exogenous mitogenic growth factors free,novel stem-cells based method to study of neurogenesis process, stem cell properties and their behaviours in a neural stem cell (NSC) niches,in addition to possibility to study the role of stem-cell niches in normal and pathological conditions, etc. Apart from further possibilities of applications in stem cell transplantation, moreover, on the other hand, the basic idea/concepts behind the method are also creating number of curiosity questions such as - whether it is possible to expand into other stem-cells niches such as osteoblasic niche, pre-metastatic niche as well as microenvironment study in model organisms?, etc., etc. A remarkable paper in the area of methods development.
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