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Nature Reports Stem Cells is no longer being updated. Although the journal club is no longer active, we hope that you will continue to enjoy the past content which is available here.

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  Cancer stem cells

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  • A luminal epithelial stem cell that is a cell of origin for prostate cancer

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      Original article citation: Nature 461," 495 - 500, (2009).

    • Categories: Cancer stem cells
    • Recommended by : Nicole DeGennaro on 10/01/2009 08:10PM GMT
      
      <p>Prostate tumours from a surprising source</p> <p>A luminal stem cell might fuel cancer</p> <p><a href="http://www.nature.com/stemcells/2009/0910/091001/full/stemcells.2009.127.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Reprogramming

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  • Nanog Is the Gateway to the Pluripotent Ground State

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      Original article citation: Cell 138," 722 - 737, (2009).

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 09/11/2009 06:56PM GMT
      
      <p>What does Nanog do?</p> <p>In embryos and induced pluripotent stem cells, Nanog sets the ground state of pluripotency</p> <p><a href="http://www.nature.com/stemcells/2009/0909/090910/full/stemcells.2009.118.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Regenerative medicine

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  • Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis

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      Original article citation: Cell Stem Cell 5," 310 - 319, (2009).

    • Categories: Regenerative medicine
    • Recommended by : Nicole DeGennaro on 09/11/2009 06:55PM GMT
      
      <p>Stem cells delay disease onset in mice with neurodegenerative disease</p> <p>Transplanted cells from biotech company detoxify poisoned brains, at least for awhile</p> <p><a href="http://www.nature.com/stemcells/2009/0909/090910/full/stemcells.2009.119.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Reprogramming

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  • The Ink4/Arf locus is a barrier for iPS cell reprogramming

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      Original article citation: Nature doi:10.1038/nature08290 (2009)

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 08/20/2009 06:09PM GMT
      
      <p>p53 prevents pluripotency</p> <p>The guardian of the genome also blocks reprogramming</p> <p><a href="http://www.nature.com/stemcells/2009/0908/090820/full/stemcells.2009.112.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Reprogramming

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  • Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

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      Original article citation: Nature doi:10.1038/nature08285 (2009)

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 08/20/2009 06:09PM GMT
      
      <p>p53 prevents pluripotency</p> <p>The guardian of the genome also blocks reprogramming</p> <p><a href="http://www.nature.com/stemcells/2009/0908/090820/full/stemcells.2009.112.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Reprogramming

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  • Linking the p53 tumour suppressor pathway to somatic cell reprogramming

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      Original article citation: Nature doi:10.1038/nature08311 (2009)

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 08/20/2009 06:08PM GMT
      
      <p>p53 prevents pluripotency</p> <p>The guardian of the genome also blocks reprogramming</p> <p><a href="http://www.nature.com/stemcells/2009/0908/090820/full/stemcells.2009.112.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Reprogramming

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  • • 
      Original article citation: doi:10.1038/nature0823

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 08/20/2009 06:08PM GMT
      
      <p>p53 prevents pluripotency</p> <p>The guardian of the genome also blocks reprogramming</p> <p><a href="http://www.nature.com/stemcells/2009/0908/090820/full/stemcells.2009.112.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Cancer stem cells

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  • Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

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      Original article citation: Cell 138," 592 - 603, (2009).

    • Categories: Cancer stem cells
    • Recommended by : Nicole DeGennaro on 08/13/2009 06:49PM GMT
      
      <p>Cancer stem cells resemble healthy stem cells</p> <p>Recent papers show how tumour-initiating cells work, and why they're hard to treat</p> <p><a href="http://www.nature.com/stemcells/2009/0908/090813/full/stemcells.2009.110.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Cancer stem cells

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  • Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

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      Original article citation: Proceedings of the National Academy of Sciences doi:10.1073/pnas.0905718106 (2009)

    • Categories: Cancer stem cells
    • Recommended by : Nicole DeGennaro on 08/13/2009 06:49PM GMT
      
      <p>Cancer stem cells resemble healthy stem cells, resist chemotherapy</p> <p>Recent papers show how tumour-initiating cells work, and why they're hard to treat</p> <p><a href="http://www.nature.com/stemcells/2009/0908/090813/full/stemcells.2009.110.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Funding

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  • And then there were two: use of hESC lines

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      Original article citation: Nat Biotechnol 27," 696 - 697, (2009).

    • Categories: Funding
    • Recommended by : Nicole DeGennaro on 08/13/2009 06:49PM GMT
      
      <p>Human embryonic stem cell research stuck on two early lines</p> <p>Field shows legacy of funding policies, early-mover advantage</p> <p><a href="http://www.nature.com/stemcells/2009/0908/090813/full/stemcells.2009.109.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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