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Nature Reports Stem Cells is no longer being updated. Although the journal club is no longer active, we hope that you will continue to enjoy the past content which is available here.

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  Regenerative medicine

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  • Comparative materials differences revealed in engineered bone as a function of cell-specific differentiation

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      Original article citation: Nat Mater doi:10.1038/nmat2505 (2009)

    • Categories: Regenerative medicine
    • Recommended by : Nicole DeGennaro on 08/13/2009 06:48PM GMT
      
      <p>Building bones from stem cells</p> <p>An analysis finds tissue-specific stem cells make chemically and functionally different bone than embryonic ones</p> <p><a href="http://www.nature.com/stemcells/2009/0908/090813/full/stemcells.2009.108.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Stem cell niches

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  • Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements

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      Original article citation: Nature doi:10.1038/nature08209 (2009)

    • Categories: Stem cell niches
    • Recommended by : Nicole DeGennaro on 07/09/2009 05:57PM GMT
      
      <p>A satellite cell surprise</p> <p>Muscle stem cells have unexpected age-dependent genetic requirements</p> <p><a href="http://www.nature.com/stemcells/2009/0907/090709/full/stemcells.2009.95.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Differentiation

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  • miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

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      Original article citation: Nature doi:10.1038/nature08195 (2009)

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 07/09/2009 05:57PM GMT
      
      <p>Add microRNA to make smooth muscle</p> <p>How a pair of microRNAs control differentiation and proliferation in a heart-cell lineage</p> <p><a href="http://www.nature.com/stemcells/2009/0907/090709/full/stemcells.2009.92.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Research tools

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  • Quantitative analysis of gene expression in a single cell by qPCR

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      Original article citation: Nat Meth 6," 503 - 506, (2009).

    • Categories: Research tools
    • Recommended by : Nicole DeGennaro on 07/09/2009 05:56PM GMT
      
      <p>Another technique for studying expression in single cells</p> <p>A reusable cDNA library offers a new approach</p> <p><a href="http://www.nature.com/stemcells/2009/0907/090709/full/stemcells.2009.98.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Embryonic stem cells

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  • In Vitro Derivation of Human Sperm from Embryonic Stem Cells

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      Original article citation: Stem Cells and Development doi:10.1089/scd.2009.0063 (2009)

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 07/09/2009 05:56PM GMT
      
      <p>Sperm-like cells made from human embryonic stem cells</p> <p>But results are only preliminary, researchers caution</p> <p><a href="http://www.nature.com/news/2009/090707/full/news.2009.646.html">See our summary on <i>Nature News<i></a></p>
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  Differentiation

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  • Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages

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      Original article citation: Nature 460," 113 - 117, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 07/02/2009 03:59PM GMT
      
      <p>Human heart progenitors identified</p> <p>Single progenitor generates diverse lineages</p> <p><a href="http://www.nature.com/stemcells/2009/0907/090702/full/stemcells.2009.93.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Embryonic stem cells

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  • A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

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      Original article citation: Nature 460," 118 - 122, (2009).

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 07/02/2009 03:58PM GMT
      
      <p>A tale of two LIFS</p> <p>Parallel pathways control pluripotency in mouse embryonic stem cells</p> <p><a href="http://www.nature.com/stemcells/2009/0907/090702/full/stemcells.2009.88.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Differentiation

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  • Cells keep a memory of their tissue origin during axolotl limb regeneration

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      Original article citation: Nature 460," 60 - 65, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 07/02/2009 03:58PM GMT
      
      <p>Regenerating limb tissue may not dedifferentiate</p> <p>Defying accepted notions, cells in newly growing salamander legs seem to remember their origin</p> <p><a href="http://www.nature.com/stemcells/2009/0907/090702/full/stemcells.2009.96.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Reprogramming

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  • Distinctive chromatin in human sperm packages genes for embryo development

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      Original article citation: Nature doi:10.1038/nature08162 (2009)

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 07/02/2009 03:58PM GMT
      
      <p>On your (histone) marks...get set...go!</p> <p>Epigenetic marks for gene activation precede fertilization</p> <p><a href="http://www.nature.com/stemcells/2009/0906/090625/full/stemcells.2009.87.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Differentiation

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  • The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting

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      Original article citation: Nature 460," 128 - 132, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 07/02/2009 03:57PM GMT
      
      <p>A new role for Oct4</p> <p>Pluripotency regulator controls X-chromosome inactivation</p> <p><a href="http://www.nature.com/stemcells/2009/0906/090625/full/stemcells.2009.89.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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