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Nature Reports Stem Cells is no longer being updated. Although the journal club is no longer active, we hope that you will continue to enjoy the past content which is available here.

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  Embryonic stem cells

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  • Metastable Pluripotent States in NOD-Mouse-Derived ESCs

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      Original article citation: Cell Stem Cell doi:10.1016/j.stem.2009.04.015

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 05/14/2009 05:55PM GMT
      
      <p>New types of embryonic stem cells generated by stabilizing pluripotency</p> <p>Molecules that replace, sustain pluripotency factors make "non-permissive" mouse strains yield stable embryonic stem cells</p> <p><a href="http://www.nature.com/stemcells/2009/0905/090514/full/stemcells.2009.74.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Embryonic stem cells

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  • MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells

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      Original article citation: Cell doi:10.1016/j.cell.2009.02.038

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 05/14/2009 05:55PM GMT
      
      <p>MicroRNA a major pluripotency repressor</p> <p>miRNA-145 represses Klf-4, Oct4 and Sox2, and is repressed by Oct4</p> <p><a href="http://www.nature.com/stemcells/2009/0905/090514/full/stemcells.2009.72.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Embryonic stem cells

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  • Chromosome instability is common in human cleavage-stage embryos

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      Original article citation: Nat Med 15," 577 - 583, (2009).

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 05/14/2009 05:50PM GMT
      
      <p>Embryos donated for research likely have chromosomal abnormalities</p> <p>Single-cell genetic analysis on embryos generated by IVF finds surprisingly high rates of rearrangements</p> <p><a href="http://www.nature.com/stemcells/2009/0905/090514/full/stemcells.2009.73.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Reprogramming

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  • Endometrium as an early sensor of in vitro embryo manipulation technologies

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      Original article citation: Proceedings of the National Academy of Sciences 106," 5687 - 5692, (2009).

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 04/30/2009 08:14PM GMT
      
      <p>Cloned embryos can't fool a womb</p> <p>The endometrium can differentiate between embryos generated by various technologies</p> <p><a href="http://www.nature.com/stemcells/2009/0904/090430/full/stemcells.2009.67.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Reprogramming

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  • The endometrium responds differently to cloned versus fertilized embryos

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      Original article citation: Proceedings of the National Academy of Sciences 106," 5681 - 5686, (2009).

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 04/30/2009 08:14PM GMT
      
      <p>Cloned embryos can't fool a womb</p> <p>The endometrium can differentiate between embryos generated by various technologies</p> <p><a href="http://www.nature.com/stemcells/2009/0904/090430/full/stemcells.2009.67.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Reprogramming

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  • Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

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      Original article citation: Cell Stem Cell doi:10.1016/j.stem.2009.04.005

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 04/30/2009 08:13PM GMT
      
      <p>Reprogramming to pluripotency without genetic engineering</p> <p>Researchers make iPS cells without inserting DNA</p> <p><a href="http://www.nature.com/stemcells/2009/0904/090430/full/stemcells.2009.65.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Reviews

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  • Structural Changes in Muscle During Contraction: Interference Microscopy of Living Muscle Fibres

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      Original article citation: Nature 173," 971 - 973, (1954).

    • Categories: Reviews and Reprogramming
    • Recommended by the Editor: Vanida Thassanapaff on 04/21/2009 02:22PM GMT
      
      Test for e-mail notifications. Please do not publish.
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  Drug discovery

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  • Virus-free induction of pluripotency and subsequent excision of reprogramming factors

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      Original article citation: Nature doi:10.1038/nature07864 (2009)

    • Categories: Drug discovery
    • Recommended by : Nicole DeGennaro on 04/03/2009 02:29PM GMT
      
      <p>iPS cell technology gains momentum in drug discovery</p> <p>iPS cells made without viral vectors may help develop drugs</p> <p><a href="http://www.nature.com/nrd/journal/v8/n4/full/nrd2867.html">See our summary on <i>Nature Reviews Drug Discovery<i></a></p>
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  Drug discovery

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  • piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

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      Original article citation: Nature doi:10.1038/nature07863 (2009)

    • Categories: Drug discovery
    • Recommended by : Nicole DeGennaro on 04/03/2009 02:28PM GMT
      
      p>iPS cell technology gains momentum in drug discovery</p> <p>iPS cells made without viral vectors may help develop drugs</p> <p><a href="http://www.nature.com/nrd/journal/v8/n4/full/nrd2867.html">See our summary on <i>Nature Reviews Drug Discovery<i></a></p>
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  Differentiation

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  • Single Lgr5 stem cells build crypt–villus structures in vitro without a mesenchymal niche

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      Original article citation: Nature doi:10.1038/nature07935 (2009)

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 04/03/2009 02:28PM GMT
      
      p>Many intestinal villi from a single stem cell, in culture</p> <p>Even without a supporting niche, intestinal stem cells can self-organize into a mini-organ in a dish</p> <p><a href="http://www.nature.com/stemcells/2009/0904/090402/full/stemcells.2009.52.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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