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Nature Reports Stem Cells is no longer being updated. Although the journal club is no longer active, we hope that you will continue to enjoy the past content which is available here.

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  Hematopoietic stem cells

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  • Haematopoietic stem cells depend on Gαs-mediated signalling to engraft bone marrow

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      Original article citation: Nature doi:10.1038/nature07859 (2009)

    • Categories: Hematopoietic stem cells
    • Recommended by : Nicole DeGennaro on 04/03/2009 02:28PM GMT
      
      <p>G-protein signalling is needed for stem cell homing</p> <p>G&alpha;s is vital for engrafting of haematopoietic stem cells</p> <p><a href="http://www.nature.com/stemcells/2009/0904/090402/full/stemcells.2009.53.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Differentiation

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  • Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells

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      Original article citation: Nature 458," 529 - 533, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 04/03/2009 02:27PM GMT
      
      <p>How tissue-specific stem cells keep their fate</p> <p>Epidermal stem cells stay skin even if alternative programs shed chromatin marks of repression</p> <p><a href="http://www.nature.com/stemcells/2009/0904/090402/full/stemcells.2009.50.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Differentiation

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  • Ezh2 Orchestrates Gene Expression for the Stepwise Differentiation of Tissue-Specific Stem Cells

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      Original article citation: Cell 136," 1122 - 1135, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 04/03/2009 02:27PM GMT
      
      <p>How tissue-specific stem cells keep their fate</p> <p>Epidermal stem cells stay skin even if alternative programs shed chromatin marks of repression</p> <p><a href="http://www.nature.com/stemcells/2009/0904/090402/full/stemcells.2009.50.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Regenerative medicine

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  • Evidence for Cardiomyocyte Renewal in Humans

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      Original article citation: Science 324," 98 - 102, (2009).

    • Categories: Regenerative medicine
    • Recommended by : Nicole DeGennaro on 04/03/2009 02:27PM GMT
      
      p>Carbon dating shows humans make new heart cells</p> <p>The cold war helps settle a hot debate about how hearts grow</p> <p><a href="http://www.nature.com/news/2009/090402/full/news.2009.232.html">See our summary on <i>Nature News<i></a></p>
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  Reprogramming

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  • Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences

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      Original article citation: Science doi:10.1126/science.1172482 (2009)

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 04/03/2009 02:26PM GMT
      
      <p>Look now! Human iPS cells with no genetic integration</p> <p>Six reprogramming factors in a plasmid reach a holy grail</p> <p><a href="http://www.nature.com/stemcells/2009/0904/090402/full/stemcells.2009.51.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Hematopoietic stem cells

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  • The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells

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      Original article citation: Nat Genet doi:10.1038/ng.350 (2009)

    • Categories: Hematopoietic stem cells
    • Recommended by : Nicole DeGennaro on 03/26/2009 09:05PM GMT
      
      p>Noncoding DNA copy number variation links to gene expression in stem cells</p> <p>A genome-wide study reveals an association between CNVs and gene activity in haematopoietic stem cells</p> <p><a href="http://www.nature.com/stemcells/2009/0903/090326/full/stemcells.2009.49.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Differentiation

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  • Neurogenin3 Is Sufficient for Transdetermination of Hepatic Progenitor Cells into Neo-Islets In Vivo but Not Transdifferentiation of Hepatocytes

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      Original article citation: Developmental Cell 16," 358 - 373, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 03/26/2009 09:04PM GMT
      
      <p>A sort of beta-cell magic: transdetermination seems easier than transdifferentiation</p> <p>A single added gene prompts liver progenitor cells to make insulin and reverse diabetes</p> <p><a href="http://www.nature.com/stemcells/2009/0903/090326/full/stemcells.2009.48.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Cancer stem cells

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  • PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells

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      Original article citation: Cell Stem Cell 4," 226 - 235, (2009).

    • Categories: Cancer stem cells
    • Recommended by : Nicole DeGennaro on 03/12/2009 08:17PM GMT
      
      <p>Treatment encourages more and more aggressive brain cancer stem cells</p> <p>Regulation is controlled by PTEN, PI3K/Akt and drug-effluxing ABCG2</p> <p><a href="http://www.nature.com/stemcells/2009/0903/090312/full/stemcells.2009.38.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Tissue stem cells

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  • Gene expression map of the Arabidopsis shoot apical meristem stem cell niche

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      Original article citation: Proceedings of the National Academy of Sciences doi:10.1073/pnas.0900843106 (2009)

    • Categories: Tissue stem cells and Research tools
    • Recommended by : Nicole DeGennaro on 03/12/2009 08:16PM GMT
      
      <p>Plant stem cells, not so different</p> <p>New technique allows gene-expression analysis</p> <p><a href="http://www.nature.com/stemcells/2009/0903/090312/full/stemcells.2009.39.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  Tissue stem cells

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  • Cardiac Fibroblasts Regulate Myocardial Proliferation through β1 Integrin Signaling

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      Original article citation: Developmental Cell 16," 233 - 244, (2009).

    • Categories: Tissue stem cells
    • Recommended by : Nicole DeGennaro on 02/27/2009 03:24PM GMT
      
      <p>Why old heart cells don't multiply</p> <p>Adult cardiac fibroblasts tell neighbouring myocytes to expand; embryonic fibroblasts say proliferate</p> <p><a href="http://www.nature.com/stemcells/2009/0902/090226/full/stemcells.2009.31.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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