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Nature Reports Stem Cells is no longer being updated. Although the journal club is no longer active, we hope that you will continue to enjoy the past content which is available here.

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  Embryonic stem cells

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  • Characterization of human embryonic stem cells with features of neoplastic progression

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      Original article citation: Nat Biotechnol 27," 91 - 97, (2009).

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 01/09/2009 07:06PM GMT
      
      <p>Robust embryonic stem cells may harbor precancerous surprises</p> <p>Particularly easy-to-culture ES cells resist differentiation</p> <p><a href="http://www.nature.com/stemcells/2009/0901/090108/full/stemcells.2009.14.html">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  Neural stem cells

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  • Focal transplantation–based astrocyte replacement is neuroprotective in a model of motor neuron disease

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      Original article citation: Nat Neurosci 11," 1294 - 1301, (2008).

    • Categories: Neural stem cells
    • Recommended by : Nicole DeGennaro on 11/13/2008 09:48PM GMT
      
      <p>Spine fix for ALS</p> <p>Q Therapeutics, others seek out the source of spinal cord degeneration</p> <p><a href="http://www.nature.com/scibx/journal/v1/n40/full/scibx.2008.962.html">See our summary in <i>SciBX: Science-Business eXchange</i></a></p>
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  Reprogramming

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  • Periodic Activation of Wnt/β-Catenin Signaling Enhances Somatic Cell Reprogramming Mediated by Cell Fusion

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      Original article citation: Cell Stem Cell 3," 493 - 507, (2008).

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 11/13/2008 09:48PM GMT
      
      <p>Exogenous aids to reprogramming and self-renewal</p> <p>Small molecules replace pluripotency gene and Wnt boosts self-renewal and reprogramming</p> <p><a href="http://www.nature.com/uidfinder/10.1038/stemcells.2008.149">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  Reprogramming

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  • Wnt-mediated self-renewal of neural stem/progenitor cells

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      Original article citation: Proceedings of the National Academy of Sciences 105," 16970 - 16975,

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 11/13/2008 09:47PM GMT
      
      <p>Exogenous aids to reprogramming and self-renewal</p> <p>Small molecules replace pluripotency gene and Wnt boosts self-renewal and reprogramming</p> <p><a href="http://www.nature.com/uidfinder/10.1038/stemcells.2008.149">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  Reprogramming

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  • Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Oct4 and Klf4 with Small-Molecule Compounds

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      Original article citation: Cell Stem Cell 3," 568 - 574, (2008).

    • Categories: Reprogramming
    • Recommended by : Nicole DeGennaro on 11/13/2008 09:47PM GMT
      
      <p>Exogenous aids to reprogramming and self-renewal</p> <p>Small molecules replace pluripotency gene and Wnt boosts self-renewal and reprogramming</p> <p><a href="http://www.nature.com/uidfinder/10.1038/stemcells.2008.149">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  Early embryogenesis

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  • Wnt Signaling Mediates Self-Organization and Axis Formation in Embryoid Bodies

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      Original article citation: Cell Stem Cell 3," 508 - 518, (2008).

    • Categories: Early embryogenesis
    • Recommended by : Nicole DeGennaro on 11/13/2008 09:47PM GMT
      
      <p>Embryoid bodies get organized</p> <p>Wnt signalling stimulates the beginnings of gastrulation</p> <p><a href="http://www.nature.com/uidfinder/10.1038/stemcells.2008.146">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  Differentiation

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  • Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

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      Original article citation: Cell Stem Cell 3," 519 - 532, (2008).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 11/13/2008 09:46PM GMT
      
      <p>Human cortical neural cell balls</p> <p>Cells cultured in embryoid bodies self-organize into specific neural subtypes</p> <p><a href="http://www.nature.com/uidfinder/10.1038/stemcells.2008.147">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  Embryonic stem cells

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  • Embryonic stem cell–specific microRNAs regulate the G1-S transition and promote rapid proliferation

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      Original article citation: Nat Genet doi:10.1038/ng.250 (2008)

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 11/07/2008 06:49PM GMT
      
      <p>MicroRNAs help embryonic stem cells grow fast</p> <p>A new screening technique identifies molecules that control the cell cycle</p> <p><a href="http://www.nature.com/uidfinder/10.1038/stemcells.2008.144">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  Embryonic stem cells

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  • De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

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      Original article citation: Nat Struct Mol Biol 15," 1176 - 1183, (2008).

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 11/07/2008 06:46PM GMT
      
      <p>Multitasking methyltransferase</p> <p>G9a silences gene expression two ways</p> <p><a href="http://www.nature.com/uidfinder/10.1038/stemcells.2008.145">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  Regenerative medicine

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  • Hmga2 Promotes Neural Stem Cell Self-Renewal in Young but Not Old Mice by Reducing p16Ink4a and p19Arf Expression

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      Original article citation: Cell 135," 227 - 239, (2008).

    • Categories: Regenerative medicine
    • Recommended by : Nicole DeGennaro on 10/30/2008 06:42PM GMT
      
      <p>Neural stem cells, young and old</p> <p>How ageing stem cells trade regeneration for tumour suppression</p> <p><a href="http://www.nature.com/uidfinder/10.1038/stemcells.2008.141">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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