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Nature Reports Stem Cells is no longer being updated. Although the journal club is no longer active, we hope that you will continue to enjoy the past content which is available here.

• Differentiation

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  • miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

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      Original article citation: Nature doi:10.1038/nature08195 (2009)

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 07/09/2009 05:57PM GMT
      
      <p>Add microRNA to make smooth muscle</p> <p>How a pair of microRNAs control differentiation and proliferation in a heart-cell lineage</p> <p><a href="http://www.nature.com/stemcells/2009/0907/090709/full/stemcells.2009.92.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages

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      Original article citation: Nature 460," 113 - 117, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 07/02/2009 03:59PM GMT
      
      <p>Human heart progenitors identified</p> <p>Single progenitor generates diverse lineages</p> <p><a href="http://www.nature.com/stemcells/2009/0907/090702/full/stemcells.2009.93.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Cells keep a memory of their tissue origin during axolotl limb regeneration

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      Original article citation: Nature 460," 60 - 65, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 07/02/2009 03:58PM GMT
      
      <p>Regenerating limb tissue may not dedifferentiate</p> <p>Defying accepted notions, cells in newly growing salamander legs seem to remember their origin</p> <p><a href="http://www.nature.com/stemcells/2009/0907/090702/full/stemcells.2009.96.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting

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      Original article citation: Nature 460," 128 - 132, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 07/02/2009 03:57PM GMT
      
      <p>A new role for Oct4</p> <p>Pluripotency regulator controls X-chromosome inactivation</p> <p><a href="http://www.nature.com/stemcells/2009/0906/090625/full/stemcells.2009.89.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Genotoxic Stress Abrogates Renewal of Melanocyte Stem Cells by Triggering Their Differentiation

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      Original article citation: Cell 137," 1088 - 1099, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 06/19/2009 02:27PM GMT
      
      <p>Cell biology: A grey's anatomy</p> <p>It seems that stress really can turn hair grey</p> <p><a href="http://www.nature.com/nature/journal/v459/n7249/full/459892a.html">See our summary in <i>Nature<i></a></p>
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  • Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal

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      Original article citation: Nat Cell Biol doi:10.1038/ncb1896 (2009)

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 06/19/2009 02:26PM GMT
      
      <p>Secreted anti-Notch ligand encourages neuron formation</p> <p>EGFL7 reported as first natural, soluble Notch receptor antagonist</p> <p><a href="http://www.nature.com/stemcells/2009/0906/090618/full/stemcells.2009.84.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Single Lgr5 stem cells build crypt–villus structures in vitro without a mesenchymal niche

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      Original article citation: Nature doi:10.1038/nature07935 (2009)

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 04/03/2009 02:28PM GMT
      
      p>Many intestinal villi from a single stem cell, in culture</p> <p>Even without a supporting niche, intestinal stem cells can self-organize into a mini-organ in a dish</p> <p><a href="http://www.nature.com/stemcells/2009/0904/090402/full/stemcells.2009.52.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells

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      Original article citation: Nature 458," 529 - 533, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 04/03/2009 02:27PM GMT
      
      <p>How tissue-specific stem cells keep their fate</p> <p>Epidermal stem cells stay skin even if alternative programs shed chromatin marks of repression</p> <p><a href="http://www.nature.com/stemcells/2009/0904/090402/full/stemcells.2009.50.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Ezh2 Orchestrates Gene Expression for the Stepwise Differentiation of Tissue-Specific Stem Cells

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      Original article citation: Cell 136," 1122 - 1135, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 04/03/2009 02:27PM GMT
      
      <p>How tissue-specific stem cells keep their fate</p> <p>Epidermal stem cells stay skin even if alternative programs shed chromatin marks of repression</p> <p><a href="http://www.nature.com/stemcells/2009/0904/090402/full/stemcells.2009.50.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Neurogenin3 Is Sufficient for Transdetermination of Hepatic Progenitor Cells into Neo-Islets In Vivo but Not Transdifferentiation of Hepatocytes

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      Original article citation: Developmental Cell 16," 358 - 373, (2009).

    • Categories: Differentiation
    • Recommended by : Nicole DeGennaro on 03/26/2009 09:04PM GMT
      
      <p>A sort of beta-cell magic: transdetermination seems easier than transdifferentiation</p> <p>A single added gene prompts liver progenitor cells to make insulin and reverse diabetes</p> <p><a href="http://www.nature.com/stemcells/2009/0903/090326/full/stemcells.2009.48.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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