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Nature Reports Stem Cells is no longer being updated. Although the journal club is no longer active, we hope that you will continue to enjoy the past content which is available here.

• Embryonic stem cells

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  • In Vitro Derivation of Human Sperm from Embryonic Stem Cells

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      Original article citation: Stem Cells and Development doi:10.1089/scd.2009.0063 (2009)

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 07/09/2009 05:56PM GMT
      
      <p>Sperm-like cells made from human embryonic stem cells</p> <p>But results are only preliminary, researchers caution</p> <p><a href="http://www.nature.com/news/2009/090707/full/news.2009.646.html">See our summary on <i>Nature News<i></a></p>
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  • A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

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      Original article citation: Nature 460," 118 - 122, (2009).

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 07/02/2009 03:58PM GMT
      
      <p>A tale of two LIFS</p> <p>Parallel pathways control pluripotency in mouse embryonic stem cells</p> <p><a href="http://www.nature.com/stemcells/2009/0907/090702/full/stemcells.2009.88.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Klf4 reverts developmentally programmed restriction of ground state pluripotency

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      Original article citation: Development 136," 1063 - 1069, (2009).

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 05/14/2009 05:56PM GMT
      
      <p>New types of embryonic stem cells generated by stabilizing pluripotency</p> <p>Molecules that replace, sustain pluripotency factors make "non-permissive" mouse strains yield stable embryonic stem cells</p> <p><a href="http://www.nature.com/stemcells/2009/0905/090514/full/stemcells.2009.74.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Metastable Pluripotent States in NOD-Mouse-Derived ESCs

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      Original article citation: Cell Stem Cell doi:10.1016/j.stem.2009.04.015

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 05/14/2009 05:55PM GMT
      
      <p>New types of embryonic stem cells generated by stabilizing pluripotency</p> <p>Molecules that replace, sustain pluripotency factors make "non-permissive" mouse strains yield stable embryonic stem cells</p> <p><a href="http://www.nature.com/stemcells/2009/0905/090514/full/stemcells.2009.74.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells

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      Original article citation: Cell doi:10.1016/j.cell.2009.02.038

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 05/14/2009 05:55PM GMT
      
      <p>MicroRNA a major pluripotency repressor</p> <p>miRNA-145 represses Klf-4, Oct4 and Sox2, and is repressed by Oct4</p> <p><a href="http://www.nature.com/stemcells/2009/0905/090514/full/stemcells.2009.72.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Chromosome instability is common in human cleavage-stage embryos

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      Original article citation: Nat Med 15," 577 - 583, (2009).

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 05/14/2009 05:50PM GMT
      
      <p>Embryos donated for research likely have chromosomal abnormalities</p> <p>Single-cell genetic analysis on embryos generated by IVF finds surprisingly high rates of rearrangements</p> <p><a href="http://www.nature.com/stemcells/2009/0905/090514/full/stemcells.2009.73.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Human embryonic stem cell phosphoproteome revealed by electron transfer dissociation tandem mass spectrometry

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      Original article citation: Proceedings of the National Academy of Sciences 106," 995 - 1000,

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 02/12/2009 07:58PM GMT
      
      <p>Characterizing the human embryonic stem cell phosphoproteome</p> <p>Study finds new phosphorylation sites on pluripotency factors Oct4 and Sox2</p> <p><a href="http://www.nature.com/stemcells/2009/0902/090212/full/stemcells.2009.29.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Reprogramming of Human Somatic Cells Using Human and Animal Oocytes

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      Original article citation: Cloning and Stem Cells doi:10.1089/clo.2009.0004 (2009)

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 02/05/2009 07:56PM GMT
      
      <p>Hybrid embryos fail to live up to stem-cell hopes</p> <p>Strategy for creating pluripotent cells called into question</p> <p><a href="http://www.nature.com/news/2009/090203/full/457642b.html">See our summary on <i>Nature<i> news</a></p>
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  • Germline Competent Embryonic Stem Cells Derived from Rat Blastocysts

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      Original article citation: Cell 135," 1299 - 1310, (2008).

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 01/09/2009 07:08PM GMT
      
      <p>Big potential in rat pluripotent stem cells</p> <p>Rat pluripotent stem cells could bring knock-out rats, reprogramming insights, and a larger menagerie of stem cells</p> <p><a href="http://www.nature.com/stemcells/2009/0901/090108/full/stemcells.2009.10.html">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  • Capture of Authentic Embryonic Stem Cells from Rat Blastocysts

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      Original article citation: Cell 135," 1287 - 1298, (2008).

    • Categories: Embryonic stem cells
    • Recommended by : Nicole DeGennaro on 01/09/2009 07:08PM GMT
      
      p>Big potential in rat pluripotent stem cells</p> <p>Rat pluripotent stem cells could bring knock-out rats, reprogramming insights, and a larger menagerie of stem cells</p> <p><a href="http://www.nature.com/stemcells/2009/0901/090108/full/stemcells.2009.10.html">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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