• Most popular
• Most recent
• Subject categories

• • Cancer stem cells
  • Commentaries
  • Differentiation
  • Drug discovery
  • Early embryogenesis
  • Embryonic stem cells
  • Ethics
  • Funding
  • Germ cells
  • Hematopoietic stem cells
  • Mesenchymal stem cells
  • Neural stem cells
  • Nuclear transfer
  • Policy
  • Regenerative medicine
  • Reprogramming
  • Research tools
  • Reviews
  • Stem cell niches
  • Tissue stem cells

Nature Reports Stem Cells is no longer being updated. Although the journal club is no longer active, we hope that you will continue to enjoy the past content which is available here.

• Germ cells

  • • 0+ votes

      0- votes

    • Log in to vote

  • Centrosome misorientation reduces stem cell division during ageing

    • Jun Cheng, Nezaket Türkel, Nahid Hemati, Margaret T. Fuller, Alan J. Hunt, Yukiko M. Yamashita
      Original article citation: Nature doi:10.1038/nature07386 (2008)

    • Categories: Stem cell niches, Tissue stem cells, Germ cells, and Regenerative medicine
    • Recommended by : Shree Singh on 10/20/2008 08:10PM GMT
      
      A remarkable paper in the area of stem cell biology. It has been proposed that a decline in stem cell function contribute to tissue ageing. However, the underlying mechanism is poorly understood until this paper wherein for the first time authors identified a novel mechanistic link between the control of stem cell polarity and the age-related decline in tissue regenerative capacity.
    • Comment on this subject: 0 comments made

  • • 1+ votes

      0- votes

    • Log in to vote

  • Asymmetric Inheritance of Mother Versus Daughter Centrosome in Stem Cell Division

    • Y. M. Yamashita, A. P. Mahowald, J. R. Perlin, M. T. Fuller
      Original article citation: Science 315," 518 - 521, (2007).

    • Categories: Tissue stem cells, Stem cell niches, Germ cells, and Regenerative medicine
    • Recommended by : Shree Singh on 05/01/2008 02:48AM GMT
      
      This is a seminal article in the stem cell field wherein for the first time the authors demonstrated that developmentally programmed asymmetric behavior and inheritance of mother and daughter centrosomes underlies the stereotyped spindle orientation and asymmetric outcome of stem cell divisions. Specifically, the mother centrosome is always inherited by the stem cell, whereas the daughter centrosome is inherited by the differentiating cell.
    • Comment on this subject: 0 comments made