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Nature Reports Stem Cells is no longer being updated. Although the journal club is no longer active, we hope that you will continue to enjoy the past content which is available here.

• Hematopoietic stem cells

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  • Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment

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      Original article citation: Nature doi:10.1038/nature08099 (2009)

    • Categories: Hematopoietic stem cells
    • Recommended by : Nicole DeGennaro on 06/19/2009 02:26PM GMT
      
      <p>Fat in bone marrow stalls engraftment</p> <p>Genetic, pharmacological interventions indicate that adipocytes stall haematopoiesis, engraftment</p> <p><a href="http://www.nature.com/stemcells/2009/0906/090618/full/stemcells.2009.85.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Hedgehog Signaling Is Dispensable for Adult Murine Hematopoietic Stem Cell Function and Hematopoiesis

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      Original article citation: Cell Stem Cell 4," 559 - 567, (2009).

    • Categories: Hematopoietic stem cells
    • Recommended by : Nicole DeGennaro on 06/11/2009 07:58PM GMT
      
      <p>Haematopoiesis, no hedgehog needed</p> <p>A surprising finding has implications for treating blood cancers and for assessing the results of genetic knockdowns</p> <p><a href="http://www.nature.com/stemcells/2009/0906/090611/full/stemcells.2009.83.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Hedgehog Signaling Is Dispensable for Adult Hematopoietic Stem Cell Function

    • 
      Original article citation: Cell Stem Cell 4," 548 - 558, (2009).

    • Categories: Hematopoietic stem cells
    • Recommended by : Nicole DeGennaro on 06/11/2009 07:58PM GMT
      
      <p>Haematopoiesis, no hedgehog needed</p> <p>A surprising finding has implications for treating blood cancers and for assessing the results of genetic knockdowns</p> <p><a href="http://www.nature.com/stemcells/2009/0906/090611/full/stemcells.2009.83.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Hematopoietic Stem Cell Development Is Dependent on Blood Flow

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      Original article citation: Cell 137," 736 - 748, (2009).

    • Categories: Hematopoietic stem cells
    • Recommended by : Nicole DeGennaro on 05/28/2009 06:03PM GMT
      
      <p>Beating heart triggers blood stem cells in the embryo</p> <p>Embryonic haematopoiesis needs flow, nitric oxide signalling</p> <p><a href="http://www.nature.com/stemcells/2009/0905/090521/full/stemcells.2009.76.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Biomechanical forces promote embryonic haematopoiesis

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      Original article citation: Nature doi:10.1038/nature08073 (2009)

    • Categories: Hematopoietic stem cells
    • Recommended by : Nicole DeGennaro on 05/28/2009 06:03PM GMT
      
      <p>Beating heart triggers blood stem cells in the embryo</p> <p>Embryonic haematopoiesis needs flow, nitric oxide signalling</p> <p><a href="http://www.nature.com/stemcells/2009/0905/090521/full/stemcells.2009.76.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Haematopoietic stem cells depend on Gαs-mediated signalling to engraft bone marrow

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      Original article citation: Nature doi:10.1038/nature07859 (2009)

    • Categories: Hematopoietic stem cells
    • Recommended by : Nicole DeGennaro on 04/03/2009 02:28PM GMT
      
      <p>G-protein signalling is needed for stem cell homing</p> <p>G&alpha;s is vital for engrafting of haematopoietic stem cells</p> <p><a href="http://www.nature.com/stemcells/2009/0904/090402/full/stemcells.2009.53.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells

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      Original article citation: Nat Genet doi:10.1038/ng.350 (2009)

    • Categories: Hematopoietic stem cells
    • Recommended by : Nicole DeGennaro on 03/26/2009 09:05PM GMT
      
      p>Noncoding DNA copy number variation links to gene expression in stem cells</p> <p>A genome-wide study reveals an association between CNVs and gene activity in haematopoietic stem cells</p> <p><a href="http://www.nature.com/stemcells/2009/0903/090326/full/stemcells.2009.49.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

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      Original article citation: Nature doi:10.1038/nature07737 (2009)

    • Categories: Hematopoietic stem cells
    • Recommended by : Nicole DeGennaro on 02/05/2009 07:59PM GMT
      
      <p>Self-renewing blood and leukaemia cells need hedgehog</p> <p>Attacking an alternative pathway might help defeat disease</p> <p><a href="http://www.nature.com/stemcells/2009/0902/090205/full/stemcells.2009.26.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Leukemic Cells Create Bone Marrow Niches That Disrupt the Behavior of Normal Hematopoietic Progenitor Cells

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      Original article citation: Science 322," 1861 - 1865, (2008).

    • Categories: Hematopoietic stem cells
    • Recommended by : Nicole DeGennaro on 01/30/2009 04:56PM GMT
      
      <p>A niche play for stem cells</p> <p>A paper by a University of Chicago team shows how leukemic cells impair normal hematopoiesis by reprogramming the hematopoietic stem (HS) cell niche</p> <p><a href="http://www.nature.com/scibx/journal/v2/n3/full/scibx.2009.80.html">See our summary on <i>SciBX</i></a></p>
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  • Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells

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      Original article citation: Nat Biotechnol 27," 84 - 90, (2009).

    • Categories: Hematopoietic stem cells
    • Recommended by : Nicole DeGennaro on 01/30/2009 04:55PM GMT
      
      <p>Blood stem cells, regulation and visualization</p> <p>The protein p53 regulates haematopoietic stem cell quiescence; a new labelling technique lets researchers watch cells divide</p> <p><a href="http://www.nature.com/stemcells/2009/0901/090129/full/stemcells.2009.23.html">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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