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Nature Reports Stem Cells is no longer being updated. Although the journal club is no longer active, we hope that you will continue to enjoy the past content which is available here.

• Tissue stem cells

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  • Gene expression map of the Arabidopsis shoot apical meristem stem cell niche

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      Original article citation: Proceedings of the National Academy of Sciences doi:10.1073/pnas.0900843106 (2009)

    • Categories: Tissue stem cells and Research tools
    • Recommended by : Nicole DeGennaro on 03/12/2009 08:16PM GMT
      
      <p>Plant stem cells, not so different</p> <p>New technique allows gene-expression analysis</p> <p><a href="http://www.nature.com/stemcells/2009/0903/090312/full/stemcells.2009.39.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Cardiac Fibroblasts Regulate Myocardial Proliferation through β1 Integrin Signaling

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      Original article citation: Developmental Cell 16," 233 - 244, (2009).

    • Categories: Tissue stem cells
    • Recommended by : Nicole DeGennaro on 02/27/2009 03:24PM GMT
      
      <p>Why old heart cells don't multiply</p> <p>Adult cardiac fibroblasts tell neighbouring myocytes to expand; embryonic fibroblasts say proliferate</p> <p><a href="http://www.nature.com/stemcells/2009/0902/090226/full/stemcells.2009.31.html">See our summary on <i>Nature Reports Stem Cells<i></a></p>
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  • Generation of a prostate from a single adult stem cell

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      Original article citation: Nature doi:10.1038/nature07427 (2008)

    • Categories: Tissue stem cells
    • Recommended by : Nicole DeGennaro on 10/30/2008 06:41PM GMT
      
      <p>Grow your own prostate</p> <p>Researchers generate new prostates from single stem cells</p> <p><a href="http://www.nature.com/uidfinder/10.1038/stemcells.2008.143">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  • Centrosome misorientation reduces stem cell division during ageing

    • Jun Cheng, Nezaket Türkel, Nahid Hemati, Margaret T. Fuller, Alan J. Hunt, Yukiko M. Yamashita
      Original article citation: Nature doi:10.1038/nature07386 (2008)

    • Categories: Stem cell niches, Tissue stem cells, Germ cells, and Regenerative medicine
    • Recommended by : Shree Singh on 10/20/2008 08:10PM GMT
      
      A remarkable paper in the area of stem cell biology. It has been proposed that a decline in stem cell function contribute to tissue ageing. However, the underlying mechanism is poorly understood until this paper wherein for the first time authors identified a novel mechanistic link between the control of stem cell polarity and the age-related decline in tissue regenerative capacity.
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  • Oligopotent stem cells are distributed throughout the mammalian ocular surface

    • François Majo, Ariane Rochat, Michael Nicolas, Georges Abou Jaoudé, Yann Barrandon
      Original article citation: Nature doi:10.1038/nature07406 (2008)

    • Categories: Tissue stem cells
    • Recommended by : Nicole DeGennaro on 10/09/2008 05:49PM GMT
      
      <p>Corneal stem cells, no exceptions</p> <p>Stem cells spread throughought the corneal surface repair general wear and tear</p> <p><a href="http://www.nature.com/uidfinder/10.1038/stemcells.2008.133">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  • The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling

    • Shigeo Takashima, Marianna Mkrtchyan, Amelia Younossi-Hartenstein, John R. Merriam, Volker Hartenstein
      Original article citation: Nature doi:10.1038/nature07156 (2008)

    • Categories: Tissue stem cells
    • Recommended by : Nicole DeGennaro on 07/24/2008 06:45PM GMT
      
      <p>Villi-nous fly guts</p> <p>Stem cells in the fly hindgut mirror the niche in mammalian villi</p> <p><a href="http://www.nature.com/uidfinder/10.1038/stemcells.2008.111">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  • Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells

    • Morgan E. Carlson, Michael Hsu, Irina M. Conboy
      Original article citation: Nature doi:10.1038/nature07034 (2008)

    • Categories: Tissue stem cells
    • Recommended by : Nicole DeGennaro on 06/19/2008 03:56PM GMT
      
      <p>A metasignalling network makes mucles age</p> <p>Regeneration is actively repressed in a metasignalling network</p> <p><a href="http://www.nature.com/uidfinder/10.1038/stemcells.2008.96">See our summary on <i>Nature Reports Stem Cells</i></a></p>
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  • Asymmetric Inheritance of Mother Versus Daughter Centrosome in Stem Cell Division

    • Y. M. Yamashita, A. P. Mahowald, J. R. Perlin, M. T. Fuller
      Original article citation: Science 315," 518 - 521, (2007).

    • Categories: Tissue stem cells, Stem cell niches, Germ cells, and Regenerative medicine
    • Recommended by : Shree Singh on 05/01/2008 02:48AM GMT
      
      This is a seminal article in the stem cell field wherein for the first time the authors demonstrated that developmentally programmed asymmetric behavior and inheritance of mother and daughter centrosomes underlies the stereotyped spindle orientation and asymmetric outcome of stem cell divisions. Specifically, the mother centrosome is always inherited by the stem cell, whereas the daughter centrosome is inherited by the differentiating cell.
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  • Elements of a Neural Stem Cell Niche Derived from Embryonic Stem Cells

    • Chris Pierret, Kathleen Spears, Jason A. Morrison, Joel A. Maruniak, Martin L. Katz, Mark D. Kirk
      Original article citation: Stem Cells and Development 16," 1017 - 1026, (2007).

    • Categories: Stem cell niches, Tissue stem cells, Drug discovery, and Research tools
    • Recommended by : Raja Radio on 12/27/2007 11:06PM GMT
      
      The authors have developed an exogenous mitogenic growth factors free,novel stem-cells based method to study of neurogenesis process, stem cell properties and their behaviours in a neural stem cell (NSC) niches,in addition to possibility to study the role of stem-cell niches in normal and pathological conditions, etc. Apart from further possibilities of applications in stem cell transplantation, moreover, on the other hand, the basic idea/concepts behind the method are also creating number of curiosity questions such as - whether it is possible to expand into other stem-cells niches such as osteoblasic niche, pre-metastatic niche as well as microenvironment study in model organisms?, etc., etc. A remarkable paper in the area of methods development.
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  • Sox17 Dependence Distinguishes the Transcriptional Regulation of Fetal from Adult Hematopoietic Stem Cells

    • I KIM, T SAUNDERS, S MORRISON
      Original article citation: Cell 130," (2007).

    • Categories: Hematopoietic stem cells and Tissue stem cells
    • Recommended by : Natalie DeWitt on 08/14/2007 05:43PM GMT
      
      Little is known about how fetal stem cells differ from those existing in the adult animal. Here they find that Sox17 is required for the maintenance of fetal and neonatal hematopoetic stem cells (HSCs), but not in those of the adult.
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