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Tissue stem cells
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p63 Is Essential for the Proliferative Potential of Stem Cells in Stratified Epithelia
- Makoto Senoo Frank McKeon,
- Original article citation: Cell 129, 523-536, (2007).
- Categories: Tissue stem cells, Reprogramming, Regenerative medicine, and Cancer stem cells
- Recommended by: Hussain Abidi on 06/10/2007 10:42PM GMT
- Reasons for recommending:
This paper showed how absence p63 can contribute to exhaustion of adult epithelial stem cells. Since 80% of all known cancers are of epithelial in origin this study is important in deciphering the mechanisms by which stem cell survivial factors are regulated in cacner cells.
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